TMEM268

Across TCGA cell cohorts, TMEM268 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM268-associated genes across cancer lineages are TNP1 and IQCF6. Each is linked with TMEM268 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM268-to-partner and partner-to-TMEM268 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNP1 grouped by TMEM268-low versus TMEM268-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM268→partner) and Y-score (partner→TMEM268) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNP1 →	+0.128	+4.415	<.001	.007	3	1
LARGE_INTESTINE	IQCF6 →	+0.311	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TNP1 by TMEM268 expression — LARGE_INTESTINE

Explore this box plot interactively →