TMEM267

Across TCGA patient cohorts, TMEM267 mutation is significantly associated with the RNA expression of many other genes, with 148 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM267-associated genes across cancer lineages are MIR8064, RPS29P32, and RNA5SP412. Each is linked with TMEM267 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM267-to-partner and partner-to-TMEM267 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8064 grouped by TMEM267-low versus TMEM267-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM267→partner) and Y-score (partner→TMEM267) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR8064 →	+0.501	+2.785	<.001	.003	3	1
UCEC	RPS29P32 →	+0.424	+2.792	.002	.006	3	1
UCEC	RNA5SP412 →	+0.688	+3.230	<.001	<.001	3	1
SKCM	RAC1P7 →	+0.082	+5.039	<.001	.003	3	1
SKCM	MTND2P14 →	+0.077	+5.408	<.001	.002	3	1
UCEC	HMX2 →	+0.981	+3.332	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 148 associations by consensus.

MIR8064 by TMEM267 expression — UCEC

Explore this box plot interactively →