TMEM267

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMEM267 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM267-associated genes across cancer lineages are Caspase-8. Each is linked with TMEM267 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM267-to-partner and partner-to-TMEM267 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-8 grouped by TMEM267-low versus TMEM267-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM267→partner) and Y-score (partner→TMEM267) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCaspase-8 →-0.265-2.973.044.03531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Caspase-8 by TMEM267 expression — UCEC

Box plot of Caspase-8 in TMEM267-low vs TMEM267-high samples in UCEC.

Explore this box plot interactively →

Exploration