TMEM265

Across TCGA patient cohorts, TMEM265 RNA expression is significantly associated with the protein abundance of many other proteins, with 2,365 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM265-associated proteins across cancer lineages are LEF1, RALGPS2_S422, and RETREG1_S151. Each is linked with TMEM265 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM265-to-partner and partner-to-TMEM265 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM265 versus LEF1 in HNSC, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM265→partner) and Y-score (partner→TMEM265) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LEF1 →	-0.587	-0.155	<.001	.003	3	2
OV	RALGPS2_S422 →	+1.007	+0.025	.001	<.001	3	2
PDAC	RETREG1_S151 →	-0.660	-0.098	.004	.005	3	2
UCEC	EPHB3 →	-0.662	-0.085	.006	<.001	3	2
LSCC	ADGRL3_T1564 →	-0.810	-0.115	.004	.003	3	2
BRCA	ZNF687_S1182 →	+0.780	+0.072	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,365 associations by consensus.

TMEM265 vs LEF1 — HNSC

Explore this scatter interactively →