TMEM263

Across TCGA cell cohorts, TMEM263 protein abundance is significantly associated with the go_rna of many other GO terms, with 3,730 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM263-associated GO terms across cancer lineages are Glycolipid catabolic process, Cotranslational protein targeting to membrane, and Protein localization to endoplasmic reticulum. Each is linked with TMEM263 in more than 9 cancer types. Because this analysis shows association rather than direction, both TMEM263-to-partner and partner-to-TMEM263 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycolipid catabolic process grouped by TMEM263-low versus TMEM263-high in BLOOD_Lymphoma.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM263→partner) and Y-score (partner→TMEM263) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Glycolipid catabolic process →	+0.164	+0.737	<.001	.006	3	10
BLOOD_Lymphoma	Cotranslational protein targeting to membrane →	+0.165	+1.162	<.001	<.001	3	8
PANCREAS	Protein localization to endoplasmic reticulum →	+0.149	+0.745	<.001	<.001	3	8
LUNG_SCLC	Modulation by symbiont of entry into host →	+0.134	+0.908	<.001	<.001	3	7
CNS	Protein N-linked glycosylation →	+0.073	+0.757	<.001	.002	2	8
BONE	Glycosphingolipid catabolic process →	+0.242	+0.676	.002	.003	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,730 associations by consensus.

Glycolipid catabolic process by TMEM263 expression — BLOOD_Lymphoma

Explore this box plot interactively →