Across TCGA cell cohorts, TMEM262 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,656 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TMEM262-associated GO terms across cancer lineages are Protein localization to vacuole, Negative regulation of autophagy, and Regulation of protein K48-linked ubiquitination. Each is linked with TMEM262 in more than 13 cancer types. Because this analysis shows association rather than direction, both TMEM262-to-partner and partner-to-TMEM262 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM262→partner) and Y-score (partner→TMEM262) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein localization to vacuole →	+0.104	+0.387	<.001	<.001	3	14
OVARY	Negative regulation of autophagy →	+0.074	+0.419	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of protein K48-linked ubiquitination →	+0.163	+0.630	.002	<.001	3	13
PANCREAS	Negative regulation of transcription initiation by RNA polymerase II →	+0.143	+0.359	<.001	.001	3	12
PANCREAS	Positive regulation of intracellular transport →	+0.072	+0.334	<.001	<.001	3	12
PANCREAS	Protein stabilization →	+0.055	+0.371	<.001	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,656 associations by consensus.

Exploration

TMEM262 survival (RNA) · tumor vs normal (RNA) · all TMEM262 data types