Across TCGA patient cohorts, TMEM26 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,151 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM26-associated proteins across cancer lineages are IKBIP, RCN3, and SEC23A. Each is linked with TMEM26 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM26-to-partner and partner-to-TMEM26 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM26→partner) and Y-score (partner→TMEM26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IKBIP →	+0.622	+0.635	.001	<.001	3	7
OV	RCN3 →	+0.731	+0.726	<.001	<.001	3	6
OV	SEC23A →	+0.428	+0.883	<.001	<.001	3	6
LUAD	SH3PXD2B →	+0.315	+0.336	<.001	<.001	3	6
OV	CNN2 →	+0.766	+0.709	<.001	<.001	3	6
GBM	COL3A1 →	+1.319	+0.716	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,151 associations by consensus.

Exploration

TMEM26 survival (RNA) · tumor vs normal (RNA) · all TMEM26 data types