Across TCGA cell cohorts, TMEM26 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,693 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TMEM26-associated GO terms across cancer lineages are Endoplasmic reticulum to Golgi vesicle-mediated transport, Process utilizing autophagic mechanism, and Autophagy. Each is linked with TMEM26 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM26-to-partner and partner-to-TMEM26 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM26→partner) and Y-score (partner→TMEM26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.073	+0.621	<.001	<.001	3	5
BONE	Process utilizing autophagic mechanism →	+0.045	+0.450	.002	.004	3	5
BONE	Autophagy →	+0.045	+0.450	.002	.004	3	5
CNS	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.042	+0.404	<.001	.005	3	4
CNS	Regulation of neuron apoptotic process →	+0.037	+0.729	.005	.008	3	4
BONE	Negative regulation of lymphocyte activation →	+0.057	+0.535	.004	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,693 associations by consensus.

Exploration

TMEM26 survival (RNA) · tumor vs normal (RNA) · all TMEM26 data types