Across TCGA pan-cancer cohorts, TMEM256P2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TMEM256P2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TMEM256P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TMEM256P2 is over-expressed in tumor.

HNSC and LUAD are the cancer types where TMEM256P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TMEM256P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.094	.021	4	view →
LUAD	All	All	+0.175	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TMEM256P2 RNA expression & survival · all TMEM256P2 data types