Across TCGA patient cohorts, TMEM256 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,487 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM256-associated proteins across cancer lineages are FXR2, UBE2G1, and ARPC3. Each is linked with TMEM256 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM256-to-partner and partner-to-TMEM256 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM256→partner) and Y-score (partner→TMEM256) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FXR2 →	+0.318	+0.641	<.001	<.001	3	5
OV	UBE2G1 →	+0.272	+0.704	.005	.001	3	4
COAD	ARPC3 →	-0.272	-0.473	.002	.004	3	4
COAD	TRMT10A →	+0.778	+0.839	.001	.001	3	3
LSCC	RABGEF1_S390 →	+0.416	+0.532	<.001	<.001	3	3
BRCA	RASSF5 →	-0.543	-0.719	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,487 associations by consensus.

Exploration

TMEM256 survival (RNA) · tumor vs normal (RNA) · all TMEM256 data types