TMEM251

Across TCGA cell cohorts, TMEM251 RNA expression is significantly associated with the RNA expression of many other genes, with 8,557 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TMEM251-associated genes across cancer lineages are GON7, NDUFB1, and MOAP1. Each is linked with TMEM251 in more than 16 cancer types. Because this analysis shows association rather than direction, both TMEM251-to-partner and partner-to-TMEM251 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM251 versus GON7 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM251→partner) and Y-score (partner→TMEM251) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	GON7 →	+1.529	+1.319	<.001	<.001	3	17
KIDNEY	NDUFB1 →	+0.941	+0.582	.001	.001	3	15
KIDNEY	MOAP1 →	+0.960	+0.698	.001	<.001	2	16
UPPER_AERODIGESTIVE_TRACT	CPSF2 →	+1.090	+0.747	<.001	<.001	3	14
BREAST	UBR7 →	+1.150	+1.023	<.001	<.001	3	14
OVARY	ATXN3 →	+1.201	+0.821	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,557 associations by consensus.

TMEM251 vs GON7 — UPPER_AERODIGESTIVE_TRACT

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