TMEM247

Across TCGA patient cohorts, TMEM247 RNA expression is significantly associated with the protein abundance of many other proteins, with 3,696 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TMEM247-associated proteins across cancer lineages are XPO5, NUP88_T525, and SMARCA4_S1452. Each is linked with TMEM247 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM247-to-partner and partner-to-TMEM247 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM247 versus XPO5 in LUAD, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM247→partner) and Y-score (partner→TMEM247) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	XPO5 →	+0.325	+0.217	.001	.001	3	3
LUAD	NUP88_T525 →	+0.393	+0.184	.007	.009	3	3
HNSC	SMARCA4_S1452 →	+0.330	+0.370	<.001	.008	3	3
HNSC	SMARCA4_S1484 →	+0.330	+0.370	<.001	.008	3	3
LUAD	ADNP →	+0.234	+0.247	<.001	<.001	3	3
HNSC	ESF1 →	+0.361	+0.221	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,696 associations by consensus.

TMEM247 vs XPO5 — LUAD

Explore this scatter interactively →