TMEM243

Across TCGA patient cohorts, TMEM243 mutation is significantly associated with the RNA expression of many other genes, with 75 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM243-associated genes across cancer lineages are PSMB7P1, MIR4672, and RN7SL647P. Each is linked with TMEM243 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM243-to-partner and partner-to-TMEM243 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMB7P1 grouped by TMEM243-low versus TMEM243-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM243→partner) and Y-score (partner→TMEM243) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PSMB7P1 →	+0.099	+3.484	<.001	.004	3	2
BLCA	MIR4672 →	+0.588	+4.363	.001	.007	3	2
SKCM	RN7SL647P →	+0.134	+7.816	<.001	.008	3	2
SKCM	RNU6-400P →	+0.333	+7.816	<.001	.008	3	1
SKCM	LINC01628 →	+0.079	+7.816	<.001	.008	3	1
UCEC	SNRPGP17 →	+0.307	+2.879	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 75 associations by consensus.

PSMB7P1 by TMEM243 expression — UCEC

Explore this box plot interactively →