TMEM241

Across TCGA cell cohorts, TMEM241 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TMEM241-associated genes across cancer lineages are TMCO5A, OR1M1, and OR2H1. Each is linked with TMEM241 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM241-to-partner and partner-to-TMEM241 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMCO5A grouped by TMEM241-low versus TMEM241-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM241→partner) and Y-score (partner→TMEM241) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TMCO5A →	+0.061	+3.866	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR1M1 →	+0.017	+3.977	.001	.005	3	1
LUNG_NSCLC_LUAD	OR2H1 →	+0.180	+3.866	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR11A1 →	+0.033	+3.734	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR12D2 →	+0.088	+4.343	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

TMCO5A by TMEM241 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →