Across TCGA patient cohorts, TMEM239 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,684 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TMEM239-associated GO terms across cancer lineages are Alpha-beta T cell activation, Alpha-beta T cell differentiation, and Lymphocyte apoptotic process. Each is linked with TMEM239 in more than 11 cancer types. Because this analysis shows association rather than direction, both TMEM239-to-partner and partner-to-TMEM239 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM239→partner) and Y-score (partner→TMEM239) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Alpha-beta T cell activation →	+0.056	+0.044	<.001	<.001	3	12
STAD	Alpha-beta T cell differentiation →	+0.060	+0.055	<.001	<.001	3	12
STAD	Lymphocyte apoptotic process →	+0.066	+0.064	<.001	<.001	3	12
STAD	Positive regulation of leukocyte proliferation →	+0.057	+0.046	<.001	<.001	3	12
STAD	Regulation of CD4-positive, alpha-beta T cell activation →	+0.050	+0.051	<.001	<.001	3	12
STAD	T cell proliferation →	+0.059	+0.061	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,684 associations by consensus.

Exploration

TMEM239 survival (RNA) · tumor vs normal (RNA) · all TMEM239 data types