Across TCGA patient cohorts, TMEM239 mutation is significantly associated with the RNA expression of many other genes, with 276 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM239-associated genes across cancer lineages are RNU7-110P, HNRNPA3P9, and SRXN1. Each is linked with TMEM239 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM239-to-partner and partner-to-TMEM239 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM239→partner) and Y-score (partner→TMEM239) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU7-110P →	+0.784	+3.286	<.001	<.001	3	2
UCEC	HNRNPA3P9 →	+0.352	+3.218	.005	.009	3	1
UCEC	SRXN1 →	+0.658	+3.343	.001	.005	3	1
UCEC	TMEM269 →	+0.267	+3.491	<.001	.002	3	1
UCEC	MIR6133 →	+0.363	+2.982	.001	.003	3	1
UCEC	RPS29P32 →	+0.509	+2.599	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 276 associations by consensus.

Exploration

TMEM239 survival (RNA) · tumor vs normal (RNA) · all TMEM239 data types