Across TCGA patient cohorts, TMEM239 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM239-associated genes across cancer lineages are CD8+ naive T-cells and Class-switched memory B-cells. Each is linked with TMEM239 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM239-to-partner and partner-to-TMEM239 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM239→partner) and Y-score (partner→TMEM239) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.031	+2.839	.020	.034	3	1
UCEC	Class-switched memory B-cells →	-0.060	-2.321	.035	.036	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

TMEM239 survival (RNA) · tumor vs normal (RNA) · all TMEM239 data types