Across TCGA cell cohorts, TMEM239 RNA expression is significantly associated with the go_rna of many other GO terms, with 416 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TMEM239-associated GO terms across cancer lineages are Regulation of type I interferon production, Regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway, and Positive regulation of mitotic cell cycle. Each is linked with TMEM239 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM239-to-partner and partner-to-TMEM239 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM239→partner) and Y-score (partner→TMEM239) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of type I interferon production →	+0.042	+0.061	<.001	.004	3	5
BONE	Regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway →	+0.140	+0.028	.005	.006	3	3
BREAST	Positive regulation of mitotic cell cycle →	+0.069	+0.063	<.001	.003	3	3
BREAST	Regulation of nucleocytoplasmic transport →	+0.062	+0.037	.002	.003	3	3
BREAST	Protein stabilization →	+0.042	+0.078	.003	.009	3	3
BREAST	Regulation of translational initiation →	+0.038	+0.065	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 416 associations by consensus.

Exploration

TMEM239 survival (RNA) · tumor vs normal (RNA) · all TMEM239 data types