TMEM237

Across TCGA cell cohorts, TMEM237 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,362 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM237-associated GO terms across cancer lineages are Positive regulation of cell cycle process, Centrosome cycle, and Positive regulation of cell cycle. Each is linked with TMEM237 in more than 18 cancer types. Because this analysis shows association rather than direction, both TMEM237-to-partner and partner-to-TMEM237 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle process grouped by TMEM237-low versus TMEM237-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM237→partner) and Y-score (partner→TMEM237) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of cell cycle process →	+0.068	+0.646	<.001	<.001	3	19
BONE	Centrosome cycle →	+0.074	+0.838	.002	<.001	3	18
BREAST	Positive regulation of cell cycle →	+0.092	+1.209	<.001	<.001	3	18
STOMACH	Mitotic nuclear division →	+0.099	+1.262	<.001	<.001	3	18
PANCREAS	Mitotic spindle organization →	+0.093	+1.135	<.001	<.001	3	18
BONE	Microtubule organizing center organization →	+0.085	+0.685	.002	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,362 associations by consensus.

Positive regulation of cell cycle process by TMEM237 expression — SOFT_TISSUE

Explore this box plot interactively →