Across TCGA patient cohorts, TMEM233 protein abundance is significantly associated with the RNA expression of many other genes, with 1,129 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM233-associated genes across cancer lineages are MFNG, GRK3, and PNPLA3. Each is linked with TMEM233 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM233-to-partner and partner-to-TMEM233 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM233→partner) and Y-score (partner→TMEM233) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MFNG →	+0.706	+0.513	.006	.006	3	1
GBM	GRK3 →	+0.940	+0.809	<.001	<.001	3	1
GBM	PNPLA3 →	-0.964	-0.665	<.001	<.001	3	1
GBM	MLC1 →	-1.268	-0.625	.003	.005	3	1
GBM	RIMS4 →	-1.823	-0.645	<.001	.007	3	1
GBM	RASSF2 →	-0.970	-0.756	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,129 associations by consensus.

Exploration

TMEM233 survival (RNA) · tumor vs normal (RNA) · all TMEM233 data types