Across TCGA cell cohorts, TMEM232 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM232-associated genes across cancer lineages are IL31, C12orf40, and OR10V1. Each is linked with TMEM232 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM232-to-partner and partner-to-TMEM232 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM232→partner) and Y-score (partner→TMEM232) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	IL31 →	+0.048	+4.212	<.001	.007	3	1
OVARY	C12orf40 →	+0.011	+4.029	<.001	.009	3	1
SKIN	OR10V1 →	+0.016	+4.437	<.001	.004	3	1
SKIN	IFITM5 →	+0.073	+3.807	.006	.007	3	1
LARGE_INTESTINE	CDX4 →	+0.011	+4.217	<.001	.001	3	1
LARGE_INTESTINE	MCHR2 →	+0.021	+3.684	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

TMEM232 survival (RNA) · tumor vs normal (RNA) · all TMEM232 data types