Across TCGA patient cohorts, TMEM231 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,742 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TMEM231-associated proteins across cancer lineages are IFT74, WDR54, and WDR19. Each is linked with TMEM231 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM231-to-partner and partner-to-TMEM231 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM231→partner) and Y-score (partner→TMEM231) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IFT74 →	+0.408	+1.151	<.001	<.001	3	7
UCEC	WDR54 →	+0.520	+1.055	<.001	<.001	3	6
UCEC	WDR19 →	+0.473	+1.217	<.001	<.001	3	5
UCEC	WDR35 →	+0.469	+1.237	<.001	<.001	3	5
UCEC	CETN2 →	+0.446	+0.986	<.001	<.001	3	5
UCEC	CFAP36 →	+0.469	+1.267	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,742 associations by consensus.

Exploration

TMEM231 survival (RNA) · tumor vs normal (RNA) · all TMEM231 data types