Across TCGA patient cohorts, TMEM231 protein abundance is significantly associated with the RNA expression of many other genes, with 4,999 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM231-associated genes across cancer lineages are C1orf158, CCDC113, and RSPH4A. Each is linked with TMEM231 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM231-to-partner and partner-to-TMEM231 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM231→partner) and Y-score (partner→TMEM231) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C1orf158 →	+1.329	+0.718	<.001	<.001	3	6
UCEC	CCDC113 →	+1.058	+0.461	<.001	<.001	3	5
UCEC	RSPH4A →	+1.383	+0.449	<.001	<.001	3	5
UCEC	PACRG →	+0.984	+0.449	<.001	<.001	3	5
UCEC	C6orf118 →	+1.578	+0.435	<.001	<.001	3	5
OV	NME5 →	+0.773	+0.557	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,999 associations by consensus.

Exploration

TMEM231 survival (RNA) · tumor vs normal (RNA) · all TMEM231 data types