TMEM230

Across TCGA patient cohorts, TMEM230 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,132 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TMEM230-associated proteins across cancer lineages are TRMT6, MAVS, and NSFL1C. Each is linked with TMEM230 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM230-to-partner and partner-to-TMEM230 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM230 versus TRMT6 in OV, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM230→partner) and Y-score (partner→TMEM230) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TRMT6 →	+0.451	+0.612	<.001	<.001	3	7
OV	MAVS →	+0.437	+0.498	<.001	.001	3	7
OV	NSFL1C →	+0.388	+0.461	.002	.002	3	7
COAD	DSTN →	+0.497	+0.608	<.001	<.001	3	6
OV	RBBP9 →	+0.454	+0.438	<.001	.001	3	6
LSCC	CRNKL1 →	+0.274	+0.416	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,132 associations by consensus.

TMEM230 vs TRMT6 — OV

Explore this scatter interactively →