TMEM230

Across TCGA patient cohorts, TMEM230 protein abundance is significantly associated with the RNA expression of many other genes, with 7,020 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM230-associated genes across cancer lineages are SEC23B, TRMT6, and NOP56. Each is linked with TMEM230 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM230-to-partner and partner-to-TMEM230 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM230 versus SEC23B in COAD, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM230→partner) and Y-score (partner→TMEM230) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SEC23B →	+0.653	+0.447	<.001	<.001	3	6
LSCC	TRMT6 →	+0.680	+0.401	<.001	<.001	3	6
OV	NOP56 →	+0.691	+0.560	<.001	<.001	3	5
OV	MGME1 →	+0.728	+0.584	<.001	<.001	3	5
COAD	TBC1D20 →	+0.556	+0.256	<.001	.004	3	5
COAD	PTPRA →	+0.687	+0.339	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,020 associations by consensus.

TMEM230 vs SEC23B — COAD

Explore this scatter interactively →