Across TCGA patient cohorts, TMEM229B mutation is significantly associated with the RNA expression of many other genes, with 67 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM229B-associated genes across cancer lineages are RPL31P47, RPS29P32, and MIR6894. Each is linked with TMEM229B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM229B-to-partner and partner-to-TMEM229B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM229B→partner) and Y-score (partner→TMEM229B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL31P47 →	+0.301	+2.899	<.001	.002	3	2
UCEC	RPS29P32 →	+0.570	+2.599	<.001	.009	3	1
UCEC	MIR6894 →	+0.557	+2.496	.005	.004	3	1
COAD	MIR1185-1 →	+0.465	+7.741	<.001	.009	3	1
UCEC	SH3GL2 →	+0.834	+3.212	.001	.009	3	1
LUSC	C4A-AS1 →	+0.014	+7.924	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

Exploration

TMEM229B survival (RNA) · tumor vs normal (RNA) · all TMEM229B data types