Across TCGA cell cohorts, TMEM229B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM229B-associated genes across cancer lineages are LCN1, PRM3, and TMEM239. Each is linked with TMEM229B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM229B-to-partner and partner-to-TMEM229B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM229B→partner) and Y-score (partner→TMEM229B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LCN1 →	+0.030	+4.922	.002	.009	3	1
BLOOD_Leukemia	PRM3 →	+0.090	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	TMEM239 →	+0.086	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

TMEM229B survival (RNA) · tumor vs normal (RNA) · all TMEM229B data types