Across TCGA patient cohorts, TMEM222 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM222-associated genes across cancer lineages are Keratinocytes and Epithelial cells. Each is linked with TMEM222 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM222-to-partner and partner-to-TMEM222 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM222→partner) and Y-score (partner→TMEM222) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Keratinocytes →	-0.016	-3.041	.033	.021	3	1
UCEC	Epithelial cells →	-0.094	-3.169	.017	.020	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

TMEM222 survival (RNA) · tumor vs normal (RNA) · all TMEM222 data types