TMEM222

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TMEM222 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,348 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TMEM222-associated GO terms across cancer lineages are Neural tube closure, Tube closure, and Positive regulation of mitophagy. Each is linked with TMEM222 in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM222-to-partner and partner-to-TMEM222 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM222→partner) and Y-score (partner→TMEM222) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUENeural tube closure →+0.077+0.654<.001<.00139
SOFT_TISSUETube closure →+0.077+0.654<.001<.00139
KIDNEYPositive regulation of mitophagy →+0.095+0.710.001.00339
LUNG_SCLCPositive regulation of post-translational protein modification →+0.069+0.612<.001<.00138
BLOOD_MyelomaPositive regulation of calcineurin-NFAT signaling cascade →+0.167+1.002<.001.00138
BLOOD_MyelomaPositive regulation of calcineurin-mediated signaling →+0.167+1.002<.001.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,348 associations by consensus.

Exploration