TMEM221

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TMEM221 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,570 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible TMEM221-associated GO terms across cancer lineages are RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, mRNA splicing, via spliceosome, and Negative regulation of respiratory burst involved in inflammatory response. Each is linked with TMEM221 in more than 9 cancer types. Because this analysis shows association rather than direction, both TMEM221-to-partner and partner-to-TMEM221 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM221→partner) and Y-score (partner→TMEM221) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHRNA splicing, via transesterification reactions with bulged adenosine as nucleophile →+0.074+0.637.009.00639
STOMACHmRNA splicing, via spliceosome →+0.074+0.637.009.00639
BREASTNegative regulation of respiratory burst involved in inflammatory response →+0.081+0.247.003.006210
BREASTNegative regulation of respiratory burst →+0.081+0.247.003.006210
OVARYEstablishment of RNA localization →+0.098+0.827<.001<.00139
STOMACHmRNA export from nucleus →+0.117+0.641.004.00639
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,570 associations by consensus.

Exploration