Across TCGA patient cohorts, TMEM220 RNA expression is significantly associated with the RNA expression of many other genes, with 19,439 significant associations in total. THYM shows the largest number of these associations.

The most reproducible TMEM220-associated genes across cancer lineages are TMEM220-AS1, MAGOH2P, and SCO1. Each is linked with TMEM220 in more than 32 cancer types. Because this analysis shows association rather than direction, both TMEM220-to-partner and partner-to-TMEM220 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM220→partner) and Y-score (partner→TMEM220) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	TMEM220-AS1 →	+1.485	+1.667	<.001	<.001	3	33
LAML	MAGOH2P →	+1.281	+0.938	<.001	<.001	3	33
ACC	SCO1 →	+0.926	+1.067	<.001	<.001	3	28
THYM	PTPN21 →	+1.869	+1.082	<.001	<.001	3	28
THYM	INCA1 →	+1.015	+0.926	<.001	<.001	3	27
THYM	AOX1 →	+2.968	+1.133	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,439 associations by consensus.

Exploration

TMEM220 survival (RNA) · tumor vs normal (RNA) · all TMEM220 data types