Across TCGA patient cohorts, TMEM220 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,973 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TMEM220-associated proteins across cancer lineages are GLOD4, ACOT8, and EIF4G1. Each is linked with TMEM220 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM220-to-partner and partner-to-TMEM220 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM220→partner) and Y-score (partner→TMEM220) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GLOD4 →	+0.316	+0.601	.001	<.001	3	7
COAD	ACOT8 →	-0.416	-0.690	<.001	<.001	3	6
BRCA	EIF4G1 →	-0.235	-0.653	.001	<.001	3	6
BRCA	FASN_S207 →	-0.620	-0.477	<.001	<.001	3	6
PDAC	HYI →	+0.403	+0.419	<.001	<.001	3	6
OV	WDR19 →	+0.360	+0.502	.002	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,973 associations by consensus.

Exploration

TMEM220 survival (RNA) · tumor vs normal (RNA) · all TMEM220 data types