Across TCGA cell cohorts, TMEM220 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,692 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM220-associated GO terms across cancer lineages are Regulation of telomere maintenance via telomerase, Positive regulation of response to oxidative stress, and Peptidyl-amino acid modification. Each is linked with TMEM220 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM220-to-partner and partner-to-TMEM220 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM220→partner) and Y-score (partner→TMEM220) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of telomere maintenance via telomerase →	+0.040	+0.708	.001	.003	3	7
OVARY	Positive regulation of response to oxidative stress →	+0.184	+1.360	.002	<.001	3	6
BREAST	Peptidyl-amino acid modification →	+0.030	+0.846	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of vacuole organization →	+0.044	+0.375	.001	.009	3	6
LUNG_NSCLC_LUAD	Negative regulation of peptide hormone secretion →	-0.075	-0.911	.008	.004	3	6
LUNG_NSCLC_LUAD	Type 2 mitophagy →	+0.106	+0.688	.005	.005	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,692 associations by consensus.

Exploration

TMEM220 survival (RNA) · tumor vs normal (RNA) · all TMEM220 data types