TMEM219

Across TCGA cell cohorts, TMEM219 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible TMEM219-associated genes across cancer lineages are SCN7A. Each is linked with TMEM219 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM219-to-partner and partner-to-TMEM219 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCN7A grouped by TMEM219-low versus TMEM219-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM219→partner) and Y-score (partner→TMEM219) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	SCN7A →	+0.020	+4.643	<.001	.008	1	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SCN7A by TMEM219 expression — URINARY_TRACT

Explore this box plot interactively →