TMEM218

Across TCGA cell cohorts, TMEM218 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,851 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TMEM218-associated GO terms across cancer lineages are Ether catabolic process, Glycerol ether catabolic process, and Platelet activating factor catabolic process. Each is linked with TMEM218 in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM218-to-partner and partner-to-TMEM218 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ether catabolic process grouped by TMEM218-low versus TMEM218-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM218→partner) and Y-score (partner→TMEM218) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Ether catabolic process →	+0.192	+0.878	<.001	<.001	3	9
OVARY	Glycerol ether catabolic process →	+0.192	+0.878	<.001	<.001	3	9
OVARY	Platelet activating factor catabolic process →	+0.192	+0.878	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Meiotic chromosome condensation →	+0.133	+0.860	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Intraciliary transport involved in cilium assembly →	+0.106	+0.702	<.001	<.001	3	8
LIVER	Protein localization to cilium →	+0.066	+1.082	.004	.006	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,851 associations by consensus.

Ether catabolic process by TMEM218 expression — OVARY

Explore this box plot interactively →