Across TCGA patient cohorts, TMEM216 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM216-associated genes across cancer lineages are Epithelial cells, Mesangial cells, and Myocytes. Each is linked with TMEM216 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM216-to-partner and partner-to-TMEM216 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM216→partner) and Y-score (partner→TMEM216) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Epithelial cells →	-0.136	-2.989	<.001	.035	3	1
UCEC	Mesangial cells →	-0.059	-3.159	.005	.020	1	1
UCEC	Myocytes →	+0.048	+3.212	.006	.010	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

TMEM216 survival (RNA) · tumor vs normal (RNA) · all TMEM216 data types