Across TCGA cell cohorts, TMEM216 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,429 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM216-associated GO terms across cancer lineages are Photoreceptor cell morphogenesis, Mitochondrial electron transport, succinate to ubiquinone, and Regulation of amyloid fibril formation. Each is linked with TMEM216 in more than 13 cancer types. Because this analysis shows association rather than direction, both TMEM216-to-partner and partner-to-TMEM216 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM216→partner) and Y-score (partner→TMEM216) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Photoreceptor cell morphogenesis →	+1.476	+1.387	<.001	<.001	3	14
BREAST	Mitochondrial electron transport, succinate to ubiquinone →	+0.080	+0.775	.004	.009	3	8
URINARY_TRACT	Regulation of amyloid fibril formation →	+0.167	+1.735	<.001	.009	3	7
OVARY	Regulation of mRNA 3'-end processing →	+0.083	+0.698	.009	.001	3	7
LUNG_NSCLC_LUAD	Cellular response to manganese ion →	+0.056	+0.871	<.001	<.001	3	6
STOMACH	NMDA selective glutamate receptor signaling pathway →	+0.217	+0.864	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,429 associations by consensus.

Exploration

TMEM216 survival (RNA) · tumor vs normal (RNA) · all TMEM216 data types