Across TCGA patient cohorts, TMEM215 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,744 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM215-associated proteins across cancer lineages are PRKAR2B, SPON1, and DCHS1. Each is linked with TMEM215 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM215-to-partner and partner-to-TMEM215 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM215→partner) and Y-score (partner→TMEM215) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PRKAR2B →	+0.625	+0.338	<.001	<.001	3	3
BRCA	SPON1 →	+0.974	+0.270	<.001	.005	3	3
BRCA	DCHS1 →	+0.506	+0.278	<.001	.006	3	3
GBM	AMPH →	+0.673	+0.369	<.001	<.001	3	3
BRCA	ITSN1 →	+0.360	+0.344	<.001	<.001	3	3
GBM	NUMBL →	+0.395	+0.402	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,744 associations by consensus.

Exploration

TMEM215 survival (RNA) · tumor vs normal (RNA) · all TMEM215 data types