TMEM208

Across TCGA pan-cancer cohorts, TMEM208 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TMEM208 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TMEM208 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TMEM208 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCEC show a favorable association.

LUAD and UCEC are the cancer types where TMEM208 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	1.000	0.857	.006	30	view →
UCEC	OS	Quartile	All	0.963	0.848	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

TMEM208–LUAD (OS)

Open the LUAD breakdown →