TMEM208

Across TCGA patient cohorts, TMEM208 protein abundance is significantly associated with the RNA expression of many other genes, with 3,662 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM208-associated genes across cancer lineages are USP11, MMP24, and LRP3. Each is linked with TMEM208 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM208-to-partner and partner-to-TMEM208 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM208 versus USP11 in UCEC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM208→partner) and Y-score (partner→TMEM208) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	USP11 →	-0.729	-0.689	<.001	.001	3	2
LSCC	MMP24 →	-0.416	-0.243	.001	.002	3	2
UCEC	LRP3 →	-0.792	-0.573	.009	.003	3	2
UCEC	ZNF589 →	-0.514	-0.538	<.001	<.001	3	2
LSCC	LRRC75A →	-0.537	-0.266	<.001	<.001	3	2
LSCC	SNHG32 →	-0.645	-0.314	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,662 associations by consensus.

TMEM208 vs USP11 — UCEC

Explore this scatter interactively →