TMEM208

Across TCGA cell cohorts, TMEM208 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM208-associated genes across cancer lineages are OR11H1, IQCF5, and MYH4. Each is linked with TMEM208 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM208-to-partner and partner-to-TMEM208 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H1 grouped by TMEM208-low versus TMEM208-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM208→partner) and Y-score (partner→TMEM208) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR11H1 →	+0.063	+5.201	<.001	.006	3	1
BLOOD_Leukemia	IQCF5 →	+0.121	+5.201	<.001	.006	3	1
BLOOD_Leukemia	MYH4 →	+0.006	+5.969	<.001	.001	3	1
BLOOD_Leukemia	FZD10 →	+0.020	+6.149	<.001	.001	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR11H1 by TMEM208 expression — BLOOD_Leukemia

Explore this box plot interactively →