Across TCGA pan-cancer cohorts, TMEM201 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TMEM201 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TMEM201 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TMEM201 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

HNSC, PDAC, and GBM are the cancer types where TMEM201 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.524	0.794	.006	15	view →
PDAC	DFS	Median	II,III,IV	0.399	0.216	.035	11	view →
GBM	OS	Quartile	All	0.691	0.416	.022	8	view →
CCRCC	DFS	Median	III,IV	1.000	0.821	.020	7	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: TMEM201 tumor-vs-normal RNA expression · all TMEM201 data types