Across TCGA patient cohorts, TMEM201 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM201-associated genes across cancer lineages are mTOR_pS2448, 14-3-3_beta, and eEF2. Each is linked with TMEM201 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM201-to-partner and partner-to-TMEM201 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM201→partner) and Y-score (partner→TMEM201) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.139	-2.095	.017	.017	3	2
UCEC	14-3-3_beta →	-0.096	-2.295	.014	.033	3	1
UCEC	eEF2 →	+0.352	+1.584	.012	.036	3	1
UCEC	EGFR_pY1068 →	-0.284	-2.502	.003	.002	3	1
UCEC	ERK2 →	+0.252	+2.502	<.001	.002	3	1
UCEC	GAPDH →	+0.547	+3.700	.009	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

TMEM201 survival (RNA) · tumor vs normal (RNA) · all TMEM201 data types