TMEM200C

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMEM200C mutation is significantly associated with the RNA expression of many other genes, with 970 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM200C-associated genes across cancer lineages are IGHD1-26, CENPM, and EMC7. Each is linked with TMEM200C in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM200C-to-partner and partner-to-TMEM200C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM200C→partner) and Y-score (partner→TMEM200C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCIGHD1-26 →+1.004+3.385.009.00732
UCECCENPM →+0.736+3.700.003.00132
UCECEMC7 →+0.537+3.732<.001<.00132
LUSCRNA5SP22 →+0.154+4.517<.001.00432
LUSCMIR620 →+0.145+4.321<.001.00632
UCECNLE1 →+0.661+3.332<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 970 associations by consensus.

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