Across TCGA cell cohorts, TMEM200C mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM200C-associated genes across cancer lineages are NANOS2, TSPAN16, and DBX2. Each is linked with TMEM200C in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM200C-to-partner and partner-to-TMEM200C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM200C→partner) and Y-score (partner→TMEM200C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NANOS2 →	+0.028	+3.455	<.001	.002	3	2
LUNG_NSCLC_LUAD	TSPAN16 →	+0.053	+4.157	.001	.003	3	2
PANCREAS	DBX2 →	+0.006	+5.000	<.001	.006	3	1
URINARY_TRACT	CHIA →	+1.476	+5.087	<.001	.004	3	1
OESOPHAGUS	PABPC5 →	+0.015	+4.857	<.001	<.001	3	1
STOMACH	OR2A25 →	+0.032	+4.129	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration

TMEM200C survival (RNA) · tumor vs normal (RNA) · all TMEM200C data types