TMEM200B

Across TCGA cell cohorts, TMEM200B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,835 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM200B-associated GO terms across cancer lineages are Regulation of cell-substrate adhesion, Positive regulation of cell-substrate adhesion, and Positive regulation of chemotaxis. Each is linked with TMEM200B in more than 9 cancer types. Because this analysis shows association rather than direction, both TMEM200B-to-partner and partner-to-TMEM200B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell-substrate adhesion grouped by TMEM200B-low versus TMEM200B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM200B→partner) and Y-score (partner→TMEM200B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell-substrate adhesion →	+0.099	+1.575	<.001	<.001	3	10
BONE	Positive regulation of cell-substrate adhesion →	+0.120	+2.099	.002	<.001	3	10
BREAST	Positive regulation of chemotaxis →	+0.113	+1.567	<.001	<.001	3	10
BONE	Regulation of focal adhesion assembly →	+0.138	+1.444	<.001	.001	3	10
BONE	Regulation of cell-substrate junction assembly →	+0.138	+1.444	<.001	.001	3	10
LUNG_NSCLC_LUSC	Transport of virus →	+0.205	+2.385	.002	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,835 associations by consensus.

Regulation of cell-substrate adhesion by TMEM200B expression — BONE

Explore this box plot interactively →