TMEM199

Across TCGA patient cohorts, TMEM199 protein abundance is significantly associated with the RNA expression of many other genes, with 7,166 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM199-associated genes across cancer lineages are PTGFR, PDPK1, and RFWD3. Each is linked with TMEM199 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM199-to-partner and partner-to-TMEM199 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM199 versus PTGFR in UCEC, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM199→partner) and Y-score (partner→TMEM199) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PTGFR →	-0.946	-0.613	.004	<.001	3	3
COAD	PDPK1 →	+0.326	+0.285	.004	.007	2	4
LSCC	RFWD3 →	+0.503	+0.246	<.001	<.001	3	3
COAD	DDX19A →	+0.309	+0.349	.005	.006	3	3
PDAC	MXD1 →	+0.721	+0.511	.002	.001	3	3
UCEC	HADHA →	-0.970	-0.779	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,166 associations by consensus.

TMEM199 vs PTGFR — UCEC

Explore this scatter interactively →