Across TCGA patient cohorts, TMEM198 RNA expression is significantly associated with the RNA expression of many other genes, with 18,418 significant associations in total. ACC shows the largest number of these associations.

The most reproducible TMEM198-associated genes across cancer lineages are CHPF, OBSL1, and STMN3. Each is linked with TMEM198 in more than 30 cancer types. Because this analysis shows association rather than direction, both TMEM198-to-partner and partner-to-TMEM198 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM198→partner) and Y-score (partner→TMEM198) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	CHPF →	+1.466	+1.249	<.001	<.001	3	31
LAML	OBSL1 →	+1.801	+0.375	<.001	<.001	3	31
ACC	STMN3 →	+1.624	+1.022	<.001	<.001	3	29
SCLC	TMEM145 →	+1.186	+0.712	<.001	<.001	3	29
SCLC	MAPK8IP2 →	+2.696	+1.098	<.001	<.001	3	29
TGCT	ZNF768 →	+1.075	+1.171	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,418 associations by consensus.

Exploration

TMEM198 survival (RNA) · tumor vs normal (RNA) · all TMEM198 data types