Across TCGA patient cohorts, TMEM198 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,088 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM198-associated proteins across cancer lineages are AP3B2_S272, BCL3, and BMP2K. Each is linked with TMEM198 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM198-to-partner and partner-to-TMEM198 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM198→partner) and Y-score (partner→TMEM198) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	AP3B2_S272 →	+1.278	+0.773	<.001	<.001	3	5
OV	BCL3 →	-0.516	-0.752	.002	<.001	3	3
GBM	BMP2K →	-0.317	-0.451	<.001	<.001	3	3
COAD	XPO1 →	+0.212	+0.804	<.001	<.001	3	3
LSCC	XPO5 →	+0.406	+0.405	.004	.002	3	3
GBM	YWHAQ →	+0.236	+0.445	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,088 associations by consensus.

Exploration

TMEM198 survival (RNA) · tumor vs normal (RNA) · all TMEM198 data types