TMEM191B

Across TCGA cell cohorts, TMEM191B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,018 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TMEM191B-associated GO terms across cancer lineages are Regulation of macrophage proliferation, Symbiont-mediated disruption of host cellular anatomical structure, and Symbiont-mediated disruption of host anatomical structure. Each is linked with TMEM191B in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM191B-to-partner and partner-to-TMEM191B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macrophage proliferation grouped by TMEM191B-low versus TMEM191B-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM191B→partner) and Y-score (partner→TMEM191B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of macrophage proliferation →	+0.205	+1.723	<.001	<.001	3	9
BREAST	Symbiont-mediated disruption of host cellular anatomical structure →	+0.115	+1.320	<.001	<.001	3	9
BREAST	Symbiont-mediated disruption of host anatomical structure →	+0.115	+1.320	<.001	<.001	3	9
OVARY	Establishment of epithelial cell apical/basal polarity →	-0.167	-1.118	.001	<.001	3	9
BREAST	Positive regulation of macrophage proliferation →	+0.164	+1.622	.003	.001	3	8
SKIN	Phospholipid biosynthetic process →	+0.034	+0.729	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,018 associations by consensus.

Regulation of macrophage proliferation by TMEM191B expression — BREAST

Explore this box plot interactively →